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            Fig 1. Skin Cross Section
Transdemal Delivery Technology

Transdermal Drug Delivery is defined as movement of substances (e.g. drugs) across stratum corneum (outer layer of skin) into systemic circulation (blood). In other words, it delivers active ingredients through the skin and directly to the desired area to achieve a better result.

Advantages of Transdemal Delivery

With the skin regarded as the impeccable external protective barrier of our body, many are sceptical of the true efficacy of transdermal delivery, especially for a hydrophilic nutrient. There are two schools of thought. One uses synthetic liposomes to encapsulate the nutrient and penetrate the skin – which is essentially a lipid bilayer. Another relies on natural oils to carry the nutrient and penetrate the skin to enter the blood stream. Lynk Biotechnologies believes that with the right formulation of natural oils, an effective transdermal delivery of health supplements is possible.

Transdermal offers a number of advantages over the oral delivery:

  • Reduce drug breakdown by by-passing the digestive system. Therefore, it requires much lower dosage compared to oral route.

  • Minimize side effects.  For example, transdermal estradiol patch doesn't cause liver damage compared to oral estradio pills.

 


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